Elacridar

产品编号: DC8301 Featured
Elacridar
结构式
143664-11-3
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中国地区超过5000个高品质化合物库存
应用领域
Elacridar 是一种有效的 P-糖蛋白 (P-glycoprotein) 和 BCRP 的抑制剂。
Cas No.: 143664-11-3
名称: N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide hydrochloride
别名: GF 120918,GF120918,GF-120918
SMILES: COC1=CC=CC2=C1NC3=C(C2=O)C=CC=C3C(=O)NC4=CC=C(C=C4)CCN5CCC6=CC(=C(C=C6C5)OC)OC
分子式: C34H33N3O5
分子量: 563.64
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: P-glycoprotein (P-gp/ABCG1) inhibitor. Blocks P-gp-mediated multidrug resistance (MDR) of the cytotoxic drugs doxorubicin and vincristine in CHRC5 cells. Also inhibits breast cancer resistance protein (BCRP/ABCG2). Orally active. For the detailed information of Elacridar hydrochloride, the solubility of Elacridar hydrochloride in water, the solubility of Elacridar hydrochloride in DMSO, the solubility of Elacridar hydrochloride in PBS buffer, the animal experiment (test) of Elacridar hydrochloride, the cell expriment (test) of Elacridar hydrochloride, the in vivo, in vitro and clinical trial test of Elacridar hydrochloride, the EC50, IC50,and affinity,of Elacridar hydrochloride, For the detailed information of Elacridar hydrochloride, the solubility of Elacridar hydrochloride in water, the solubility of Elacridar hydrochloride in DMSO, the solubility of Elacridar hydrochloride in PBS buffer, the animal experiment (test) of Elacridar hydrochloride, the cell expriment (test) of Elacridar hydrochloride, the in vivo, in vitro and clinical trial test of Elacridar hydrochloride, the EC50, IC50,and affinity,of Elacridar hydrochloride, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC8301 Elacridar Elacridar 是一种有效的 P-糖蛋白 (P-glycoprotein) 和 BCRP 的抑制剂。