| References: |
MELK (maternal embryonic leucine zipper kinase) is a novel therapeutic target For breast cancer and also reported to be highly upregulated in multiple types of human cancer. OTSSP167 is a highly potent MELK inhibitor (IC50 of 0.41 nM) and inhibited the phosphorylation of PSMA1 (proteasome subunit alpha type 1) and DBNL (drebrin-like). MELK inhibitor OTSSP167 should be a promising compound possibly to suppress the growth of tumor-initiating cells and be applied For treatment of a wide range of human cancer.For the detailed information of OTSSP167 HCl Salt, the solubility of OTSSP167 HCl Salt in water, the solubility of OTSSP167 HCl Salt in DMSO, the solubility of OTSSP167 HCl Salt in PBS buffer, the animal experiment (test) of OTSSP167 HCl Salt, the cell expriment (test) of OTSSP167 HCl Salt, the in vivo, in vitro and clinical trial test of OTSSP167 HCl Salt, the EC50, IC50,and Affinity of OTSSP167 HCl Salt, Please contact DC Chemicals. |
