| DC26231 |
Furin Inhibitor II
|
Hexa-D-arginine (Furin Inhibitor II) 是一种稳定的 furin 抑制剂，对 furin，PACE4 和 PC1 的 Ki 值分别为 106 nM，580 nM 和 13.2 μM。Hexa-D-arginine 在体外和体内均可阻断假单胞菌外毒素 A 和炭疽毒素的毒性。 |
| DC9619 |
Nafamostat (mesylate)
|
Nafamostat mesylate, a synthetic serine protease inhibitor, is an anticoagulant,showed highly potent activity against COVID-19(SARS-COV-2). |
| DC7992 |
PX 12
|
PX-12(IV-2) is an irreversible inhibitor of Thioredoxin-1(Trx-1) currently in clinical development as an antitumor agent; IC50=7 uM in Hela, MTT assay, 72 h. |
| DC23149 |
Oseltamivir acid
|
Oseltamivir acid (GS 4071, Ro 64-0802, Oseltamivir carboxylate) is a potent inhibitor of influenza neuraminidase (NA) with Ki of <1 nM for both A and B strains.. |
| DC21567 |
Triazavirin
|
Triazavirin (Riamilovir sodium dihydrate) is a broad-spectrum antiviral agent targeting influenza viruses, lassa virus, TBEV and Ebola virus. |
| DC2107 |
Gemcitabine HCl (Gemzar,LY188011)
|
Gemcitabine Hydrochloride (Gemzar) is a DNA synthesis inhibitor ,showed potent activity against COVID-19(SARS-COV-2) with EC50 MERS-COV(1.216), SARS-COV(4.957). |
| DC26232 |
DX 600（ACE2 Inhibitor）
|
DX600 is a potent and selective peptide inhibitor of angiotensin-converting enzyme 2 (ACE2; Kis = 2.8, 200, and 1,200 nM for recombinant, human, and murine ACE2, respectively). |
| DC26230 |
Furin Inhibitor I
|
Furin inhibitor I is a selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases, including furin/SPC1 (Ki = ~1 nM), SPC2/PC2 (Ki = 0.36 nM), SPC3/PC1/PC3 (Ki = 2.0 nM), SPC4/PACE4 (Ki = 3.6 nM), SPC6/PC5/PC6, and SPC7/LP |
| DC24010 |
Plpro-IN-6
|
PLpro inhibitor是PLpro抑制剂，IC50为2.6 uM。 |
| DC22629 |
GRL-0617
|
GRL0617 是一种强效、选择性和竞争性的 SARS-CoV PLpro/deubiquitinase 的非共价抑制剂，其 IC50 值为 0.6 μM，Ki 值为 0.49 μM. |
