PE859
产品编号: DC10289
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中国地区超过5000个高品质化合物库存
应用领域
PE859是tau和Aβ积累的有效抑制剂，IC50值分别为0.66 和1.2 μM。
| Cas No.: |
1402727-29-0 |
| 名称: |
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| 别名: |
PE-859; PE 859 |
| SMILES: |
COC1=CC(OCC2=NC=CC=C2)=CC=C1/C=C/C3=CC(/C=C/C4=CC5=C(C=C4)C=CN5)=NN3 |
| 分子式: |
C28H24N4O2 |
| 分子量: |
448.52 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
PE859 inhibits the heparin-induced aggregation of both 3RMBD and full length tau in a concentration-dependent manner. In each assay, the IC50 values calculated at the last measurement periods are 0.81 μM, and 2.23 μM, respectively. PE859 inhibits tau aggr |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_169_DC10289_1402727-29-0 |
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COA
| LOT NO. |
DOWNLOAD |
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询盘
