KPT-330(Selinexor)

产品编号: DC7067 Featured
KPT-330(Selinexor)
结构式
1393477-72-9
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中国地区超过5000个高品质化合物库存
应用领域
KPT-330, analog of KPT-185, is an orally bioavailable selective CRM1 inhibitor.
Cas No.: 1393477-72-9
名称: (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide
别名: KPT330; KPT 330
SMILES: C1=CN=C(C=N1)NNC(=O)/C=C\N2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F
分子式: C17H11F6N7O
分子量: 443.31
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: As the clinical candidate analog of KPT-185, KPT-330 exhibits similar effects on the viability of T-ALL cells and elicits rapid apoptotic response. KPT-330 also reduces cell growth in MOLT-4, Jurkat, HBP-ALL, KOPTK-1, SKW-3, and DND-41 cell lines, with IC
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC7067 KPT-330(Selinexor) KPT-330, analog of KPT-185, is an orally bioavailable selective CRM1 inhibitor.