| References: |
In porcine aortic vascular smooth muscle cells, BQ-123 selectively inhibits ETA-mediated contraction. In rat vascular smooth muscle cells, BQ-123 inhibits endothelin-1-induced phosphoinositide breakdown and DNA synthesis. In rats, BQ-123 (1 mg/kg, i.v.) ameliorates myocardial ischemic-reperfusion injury. In rats with pentylenetetrazole (PTZ)-induced tonic-clonic seizures, BQ-123 (3 mg/kg, i.v.) potently impedes the formation and spread of seizure. In pregnant C57BL/6 mice, BQ-123 (6.7 mg/kg, i.p.) prevents LPS-induced preterm birth in mice via the induction of uterine and placental IL-10. [5] For the detailed information of BQ-123, the solubility of BQ-123 in water, the solubility of BQ-123 in DMSO, the solubility of BQ-123 in PBS buffer, the animal experiment (test) of BQ-123, the cell expriment (test) of BQ-123, the in vivo, in vitro and clinical trial test of BQ-123, the EC50, IC50,and affinity,of BQ-123, For the detailed information of BQ-123, the solubility of BQ-123 in water, the solubility of BQ-123 in DMSO, the solubility of BQ-123 in PBS buffer, the animal experiment (test) of BQ-123, the cell expriment (test) of BQ-123, the in vivo, in vitro and clinical trial test of BQ-123, the EC50, IC50,and affinity,of BQ-123, Please contact DC Chemicals. |
