Cas No.: | 1351761-44-8 |
名称: | |
别名: | GNE7915; GNE 7915 |
SMILES: | C(C1=CC(OC)=C(NC2=NC=C(C(F)(F)F)C(NCC)=N2)C=C1F)(N1CCOCC1)=O |
分子式: | C19H21F4N5O3 |
分子量: | 443.4 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | GNE-7915 is a highly potent, selective, and brain-penetrable LRRK2 small molecule inhibitor with IC50 of 9 nM in cellular LRRK2 assay; > 100 fold selectivity against a panel of 187 kianses(Ki). IC50 value: 9 nM (cellular assay) Target: LRRK2 GNE-7915 dem |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |