Cas No.: | 1285515-21-0 |
名称: | |
别名: | GSK2578215A,GSK-2578215A,GSK 2578215A |
SMILES: | C1=CC=C(C=C1)COC2=C(C=C(C=C2)C3=CC(=NC=C3)F)C(=O)NC4=CN=CC=C4 |
分子式: | C24H18FN3O2 |
分子量: | 399.42 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | GSK2578215A is a potent and highly selective LRRK2 inhibitor; exhibits IC50s of around 10 nM against both wild-type LRRK2 and the G2019S mutant. IC50 value: ~10 nM(wt-LRRK2; LRRK2 G2019S) Target: LRRK2 inhibitor GSK2578215A exhibits exceptionally high sel |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |