Romidepsin(FK-228)

产品编号: DCAPI1434
Romidepsin(FK-228)
结构式
128517-07-7
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中国地区超过5000个高品质化合物库存
应用领域
Romidepsin strongly inhibits HDAC1 and HDAC2 with IC50 of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC50 25 nM and 790 nM, respectively.
Cas No.: 128517-07-7
名称:
别名: FK 228;  FR 901228;  NSC 630176;  depsipeptide,FK228
SMILES: O=C(N/C(C(N[C@H]1C(C)C)=O)=CC)[C@@](NC([C@](C(C)C)([H])NC(C2)=O)=O)([H])CSSCC/C=C[C@@]2([H])OC1=O
分子式: C24H36N4O6S2
分子量: 540.7
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References:
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
TITLE DOWNLOAD
MSDS_3588_DCAPI1434_128517-07-7
COA
LOT NO. DOWNLOAD
产品编号 产品名称 应用领域
DCAPI1434 Romidepsin(FK-228) Romidepsin strongly inhibits HDAC1 and HDAC2 with IC50 of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC50 25 nM and 790 nM, respectively.
DC7048 Ricolinostat (ACY-1215) Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM; >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2.
DC5178 Tubacin (BML-GR362) Tubacin is a selective inhibitor of HDAC6 via inhibition of the second deacetylase domain (DD2).