TAK-438
产品编号: DC7306
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应用领域
TAK-438是有一种口服活性的钾竞争性酸阻断剂,抑制H+, K+-ATPase的 IC50 值为19 nM。
Cas No.: |
1260141-27-2 |
名称: |
C17H16FN3O2S.C4H4O4 |
别名: |
TAK 438; TAK438 |
SMILES: |
N(S(C1=CC=CN=C1)(=O)=O)1C(C2=CC=CC=C2F)=CC(CNC)=C1.C(O)(=O)/C=C/C(O)=O |
分子式: |
C17H16FN3O2S.C4H4O4 |
分子量: |
461.46 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
TAK-438 is a pyrrole derivative with a chemical structure that is completely different from the P-CABs developed to date. TAK-438 inhibits gastric H+, K+-ATPase activity in a concentration-dependent manner. Under neutral conditions (pH 7.5), the inhibitor |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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