KS176
产品编号: DC9256
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应用领域
KS176是一种选择性的高活性乳腺癌耐药蛋白多药转运通道 (BCRP) 抑制剂(在Pheo A和Hoechst检测中IC50值分别为0.59和1.39 μM)。对P-gp和MRP1没有抑制活性。
Cas No.: |
1253452-78-6 |
名称: |
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别名: |
KS-176,KS 176 |
SMILES: |
C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)CCO)NC(=O)C3=CC=C(C=C3)[N+](=O)[O-] |
分子式: |
C22H19N3O5 |
分子量: |
405.4 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1. |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
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MSDS_2585_DC9256_1253452-78-6 |
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COA
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