| References: |
NR2C/NR2D-selective NMDA receptor non-competitive antagonist (IC50 values are 3, 6, 229, and >300, >300 μM for NR2D, NR2C, NR2A, NR2B, and GluR1, respectively). Requires binding of glutamate to the GluN2 subunit. QNZ46 inhibits NMDA receptor function in a noncompetitive and voltage-independent manner by an unconventional mechanism that requires binding of glutamate to the GluN2 subunit, but not glycine binding to the GluN1 subunit. For the detailed information of QNZ46, the solubility of QNZ46 in water, the solubility of QNZ46 in DMSO, the solubility of QNZ46 in PBS buffer, the animal experiment (test) of QNZ46, the cell expriment (test) of QNZ46, the in vivo, in vitro and clinical trial test of QNZ46, the EC50, IC50,and affinity,of QNZ46, For the detailed information of QNZ46, the solubility of QNZ46 in water, the solubility of QNZ46 in DMSO, the solubility of QNZ46 in PBS buffer, the animal experiment (test) of QNZ46, the cell expriment (test) of QNZ46, the in vivo, in vitro and clinical trial test of QNZ46, the EC50, IC50,and affinity,of QNZ46, Please contact DC Chemicals. |
