Cas No.: | 1236699-92-5 |
名称: | |
别名: | Pimasertib; MSC1936369B; AS-703026; AS 703026, Pimasertib; MSC1936369B; AS-703026; AS 703026 |
SMILES: | FC1=C(C=CC(I)=C1)NC2=CN=CC=C2C(NC[C@@H](CO)O)=O |
分子式: | C15H15FIn3O3 |
分子量: | 431.2 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | AS703026(Pimasertib) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines. IC50 value: Target: MEK1/2 in vitro: AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor that |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |