kb NB 142-70

产品编号: DC8084 Featured
kb NB 142-70
结构式
1233533-04-4
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中国地区超过5000个高品质化合物库存
应用领域
kb NB 142-70 是一种有效的 PKD 抑制剂,对 PKD1,PKD2 和 PKD3 的 IC50 值分别为 28.3 nM,58.7 nM 和 53.2 nM;kb NB 142-70 同时具有抗肿瘤活性。
Cas No.: 1233533-04-4
名称: 9-Hydroxy-3,4-dihydro-2H-[1]-benzothiolo[2,3-f][1,4]thiazepin-5-one
别名:
SMILES: C1CSC2=C(C(=O)N1)SC3=C2C=C(C=C3)O
分子式: C11H9NO2S2
分子量: 251.32
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: kb NB 142-70 is a selective protein kinase D (PKD) inhibitor. Demonstrates a 7-fold increase in inhibition potency as an analog of CID 755673. Reported to demonstrate prominent cytotoxic and anti-proliferative effects in vitro. Additionally noted to inhibit cell migration and invasion in a prostate cancer cell line. kb NB 142-70 is an inhibitor of PKC μ, PKC ν and PKD2. For the detailed information of kb NB 142-70, the solubility of kb NB 142-70 in water, the solubility of kb NB 142-70 in DMSO, the solubility of kb NB 142-70 in PBS buffer, the animal experiment (test) of kb NB 142-70, the cell expriment (test) of kb NB 142-70, the in vivo, in vitro and clinical trial test of kb NB 142-70, the EC50, IC50,and affinity,of kb NB 142-70, For the detailed information of kb NB 142-70, the solubility of kb NB 142-70 in water, the solubility of kb NB 142-70 in DMSO, the solubility of kb NB 142-70 in PBS buffer, the animal experiment (test) of kb NB 142-70, the cell expriment (test) of kb NB 142-70, the in vivo, in vitro and clinical trial test of kb NB 142-70, the EC50, IC50,and affinity,of kb NB 142-70, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC8084 kb NB 142-70 kb NB 142-70 是一种有效的 PKD 抑制剂,对 PKD1,PKD2 和 PKD3 的 IC50 值分别为 28.3 nM,58.7 nM 和 53.2 nM;kb NB 142-70 同时具有抗肿瘤活性。