| Cas No.: | 1223397-11-2 |
| 名称: | 3-hydroxy-benzoic acid, (3-fluoro-1,2-phenylene)ester |
| 别名: | WZB117,WZB-117,WZB 117 |
| SMILES: | OC1=CC=CC(C(OC2=CC=CC(F)=C2OC(C3=CC(O)=CC=C3)=O)=O)=C1 |
| 分子式: | C20H13FO6 |
| 分子量: | 368.3 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
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| In Vitro: | |
| References: | WZB117 is an irreversible inhibitor of glucose transporter 1 (Glut1) that blocks glucose transport in diverse cancer cells (IC50 = ~0.6 µM), reducing extracellular lactate and intracellular ATP levels. It inhibits cancer cell proliferation (IC50s = 5-10 µM), resulting in cell cycle arrest, senescence, and necrosis or apoptosis. |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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