TPPU

产品编号: DC10025 Featured
TPPU
结构式
1222780-33-7
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中国地区超过5000个高品质化合物库存
应用领域
TTPU是可溶性环氧化物水解酶(sEH)抑制剂,对猴子和人类的IC50值分别为37和3.7 nM。
Cas No.: 1222780-33-7
名称: N-[1-(1-oxopropyl)-4-piperidinyl]-N’-[4-(trifluoromethoxy)phenyl)-urea
别名:
SMILES: CCC(=O)N1CCC(CC1)NC(=O)NC2=CC=C(C=C2)OC(F)(F)F
分子式: C16H20F3N3O3
分子量: 359.3
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: TPPU is a potent inhibitor of both human and mouse sEH (IC50 = 3.7 and 2.8 nM, respectively). The pharmacokinetics of this compound are dramatically superior to those of the 1-adamantylurea based inhibitors, like AUDA.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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