| Cas No.: | 1220646-23-0 |
| 名称: | N2,N6,N6,5,7-pentamethyl-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine-2,6-diamine |
| 别名: | AVN-492; AVN 492; AVN492;1220646-23-0 |
| SMILES: | CNC1=NN2C(N=C(C)C(N(C)C)=C2C)=C1S(C3=CC=CC=C3)(=O)=O |
| 分子式: | C17H21N5O2S |
| 分子量: | 359.14 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
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| In Vitro: | |
| References: | AVN-492 is a potent and selective 5-HT6R Antagonist. The affinity of AVN-492 to bind to 5-HT6R (Ki = 91 pM) was more than three orders of magnitude higher than that to bind to the only other target, 5-HT2BR, (Ki = 170 nM). AVN-492 demonstrates good in vitro and in vivo ADME profile with high oral bioavailability and good brain permeability in rodents. |
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| References: |
MSDS
| TITLE | DOWNLOAD |
| MSDS_759_DC11399_1220646-23-0 |
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COA
| LOT NO. | DOWNLOAD |
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