| Cas No.: | 1218778-77-8 |
| 名称: | [1,1'-Biphenyl]-3-carboxamide,N-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-,rel- |
| 别名: | NVP-LDE225,LDE225 |
| SMILES: | C(C1=CC=C(OC(F)(F)F)C=C1)1=CC=CC(C(NC2=CC=C(N3C[C@@H](C)O[C@@H](C)C3)N=C2)=O)=C1C |
| 分子式: | C26H26F3N3O3.2H3Po4 |
| 分子量: | 681.5 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | LDE225 inhibits TM3 luciferized cell line with 0.6 nM and 8 nM, at the presence of 1 nM and 25 nM Hh agonist Ag1.5, respectively. LDE225 is highly bound to mouse, rat, and human plasma proteins (>99%) and moderately bound to dog and monkey plasma proteins |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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