PF-04971729 (Ertugliflozin)
产品编号: DC3108
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应用领域
Ertugliflozin (PF-04971729) 是有效的、选择性的、具有口服活性的钠离子依赖的葡萄糖协同转运蛋白2 (SGLT2) 的抑制剂。其对h-SGLT2 的 IC50 值为0.877 nM。有治疗2型糖尿病的潜能。
| Cas No.: |
1210344-57-2 |
| 名称: |
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| 别名: |
PF04971729,PF 04971729 (Ertugliflozin) |
| SMILES: |
C1=CC([C@@]23O[C@@](CO)(CO2)[C@H](O)[C@@H](O)[C@@H]3O)=CC(CC2=CC=C(OCC)C=C2)=C1Cl |
| 分子式: |
C22H25ClO7 |
| 分子量: |
436.9 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
PF-04971729, a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2, is currently in phase 2 trials For the treatment of diabetes mellitus. Inhibitory effects against the organic cation transporter 2-mediated uptake of [14C]met |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
