MK-1064
产品编号: DC9966
Featured
我们的合作伙伴:
中国地区超过5000个高品质化合物库存
应用领域
MK-1064是一个选择性的2-SORA拮抗剂，可用于失眠患者的研究。
| Cas No.: |
1207253-08-4 |
| 名称: |
|
| 别名: |
MK1064,MK 1064 |
| SMILES: |
COC1=C(N=C(C=C1)CNC(=O)C2=C(N=CC(=C2)C3=CC(=CN=C3)Cl)C4=CC=CC=N4)OC |
| 分子式: |
C24H20ClN5O3 |
| 分子量: |
461.9 |
| 纯度: |
|
| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
|
| In Vivo: |
|
| In Vitro: |
|
| References: |
MK-1064 is a selective orexin 2 receptor antagonist (2-SORA) for the research of insomnia. MK-1064 promotes sleep and increases both rapid eye movement (REM) and non-REM (NREM) sleep in rats at OX2R occupancies higher than the range observed for dual orexin receptor antagonists. MK-1064 increases NREM and REM sleep in dogs without inducing cataplexy. The reference for animal administration is 30 mg/kg. |
| Kinase Assay: |
|
| Cell Assay: |
|
| Animal Administration: |
|
| References: |
|
MSDS
| TITLE |
DOWNLOAD |
| MSDS_2917_DC9966_1207253-08-4 |
|
COA
| LOT NO. |
DOWNLOAD |
|
|
询盘
