Cas No.: | 1194961-19-7 |
名称: | 2-(((1R,2S)-2-aminocyclohexyl)amino)-4- (m-tolylamino)pyrimidine-5-carboxamide |
别名: | PRT 060318 ,PRT060318,PRT 318,PRT-318,PRT318 |
SMILES: | O=C(C1=CN=C(N[C@H]2[C@@H](N)CCCC2)N=C1NC3=CC=CC(C)=C3)N |
分子式: | C18H24N6O |
分子量: | 340.4 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
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In Vitro: | |
References: | PRT-060318, also known as PRT318 or P142–76, is a novel selective inhibitor of the tyrosine kinase Syk, as an approach to HIT treatment. PRT318 completely inhibited HIT immune complex-induced aggregation of both human and transgenic HIT mouse platelets. |
Kinase Assay: | |
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Animal Administration: | |
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