ML-109
产品编号: DC12333
Featured
我们的合作伙伴:
中国地区超过5000个高品质化合物库存
应用领域
ML-109 是有效的、促甲状腺激素受体 (TSHR) 的全激动剂，其 EC50 值为 40 nM。
| Cas No.: |
1186649-91-1 |
| 名称: |
|
| 别名: |
|
| SMILES: |
CC(NC1=CC=C(OCC2=CC(C(N3CC4=CC=CC=C4)NC5=C(C(O)=CC=C5)C3=O)=CC=C2OC)C=C1)=O |
| 分子式: |
C31H29N3O5 |
| 分子量: |
523.58 |
| 纯度: |
|
| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
|
| In Vivo: |
|
| In Vitro: |
|
| References: |
In Vitro
ML-109 (Compound 2) is a full agonist at TSHR with an EC50 of 40 nM and, like compound 1, it has no activity at FSHR or LHCGR. ML-109 contains an aminal, a functional group that is subject to hydrolysis and/or other degradation mechanisms. ML-109 is surprisingly stable at neutral and basic conditions (t1/2 of ~16 h) but is found to degrade at low pH (t1/2 of ~3 h). |
| Kinase Assay: |
|
| Cell Assay: |
|
| Animal Administration: |
|
| References: |
|
MSDS
| TITLE |
DOWNLOAD |
| MSDS_3091_DC12333_1186649-91-1 |
|
COA
| LOT NO. |
DOWNLOAD |
|
|
询盘
