CERC-501(LY-2456302,Aticaprant)
产品编号: DC9765
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应用领域
Aticaprant (CERC-501) 是一种有效地可渗透中枢神经的kappa opioid受体拮抗剂，Ki值为0.807 nM。
| Cas No.: |
1174130-61-0 |
| 名称: |
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| 别名: |
LY2456302,LY 2456302，CERC501，CERC 501 |
| SMILES: |
C1=C(C)C=C([C@H]2CCCN2CC2=CC=C(OC3=C(F)C=C(C(=O)N)C=C3)C=C2)C=C1C |
| 分子式: |
C26H27FN2O2 |
| 分子量: |
418.5 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
CERC-501 (originally known as LY-2456302) is a potent, selective, short-acting (non-"inactivating") antagonist of the κ-opioid receptor (KOR) (Ki = 0.81 nM vs. 24.0 nM and 155 nM for the μ-opioid receptor (MOR) and δ-opioid receptor (DOR), respectively; ~30-fold selectivity for the KOR). |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
