Cas No.: | 1173097-76-1 |
名称: | 1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene |
别名: | U0126-EtOH; U 0126; U-0126 |
SMILES: | CCO.C1=CC=C(C(=C1)N)SC(=C(C#N)C(=C(N)SC2=CC=CC=C2N)C#N)N |
分子式: | C18H16N6S2.C2H6O |
分子量: | 426.56 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | Potent and selective non-competitive inhibitor of MAP kinase kinase. Inhibits MEK-1 and MEK-2 (IC50values of 0.07 and 0.06 μM respectively) with little or no effect on the activities of PKC, Abl, Raf, MEKK, ERK, JNK, MKK-3, MKK-4/SEK, MKK-6, Cdk2 or Cdk4. |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |