Cas No.: | 1166227-08-2 |
名称: | (2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide |
别名: | |
SMILES: | CC1=C(C2=CSC(C(C)(C)C)=N2)SC(NC(N3CCC[C@H]3C(N)=O)=O)=N1 |
分子式: | C17H23N5O2S2 |
分子量: | 393.53 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | In addition to the wild-type p110α, A66 also potently inhibits the oncogenic Forms of p110α such as p110α E545K and p110α H1047R with IC50 of 30 nM and 43 nM, respectively. Unlike PIK-75, A66 displays >100 fold selectivity For p110α over other class-I P |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |