LGD-4033
产品编号: DC7633
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应用领域
LGD-4033是一种新型的非类固醇, 口服SARM, 以高亲和力 (Ki为1 nM) 和选择性与雄激素受体结合。
Cas No.: |
1165910-22-4 |
名称: |
4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile |
别名: |
LGD4033, 4-((R)-2-((R)-2,2,2-Trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-(trifluoromethyl)benzonitrile |
SMILES: |
C(#N)C1=CC=C(N2CCC[C@H]2[C@H](O)C(F)(F)F)C=C1C(F)(F)F |
分子式: |
C14H12F6N2O |
分子量: |
338.248299 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vitro: |
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References: |
Pre-clinical Modeling of LGD-4033 Efficacy: In castrated male rats,LGD-4033 increased levator ani muscle weight in a dose dependent manner when administered via continuous release osmotic minipump. Osmotic minipump dosing was utilized to mimic the long ha |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
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MSDS_1865_DC7633_1165910-22-4 |
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