CI994 (Tacedinaline)

产品编号: DC2060 Featured
CI994 (Tacedinaline)
结构式
112522-64-2
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中国地区超过5000个高品质化合物库存
应用领域
Tacedinaline (N-acetyldinaline) 是组蛋白脱乙酰酶(HDAC)的抑制剂,抑制重组HDAC 1, 2 and 3的 IC50 值分别为0.9,0.9,1.2 μM。
Cas No.: 112522-64-2
名称: Benzamide, 4-(acetylamino)-N-(2-aminophenyl)-
别名: PD-123654,CI-994,PD123654
SMILES: CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N
分子式: C15H15N3O2
分子量: 269.3
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Description of Tacedinaline: Tacedinaline, also known as CI-944, is an orally bioavailable substituted benzamide derivative with potential antineoplastic activity. Tacedinaline inhibits histone deacetylation, which may result in histone hyperacetylation, followed by the induction of differentiation, the inhibition of cell proliferation, and apoptosis in susceptible tumor cell populations. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) For the detailed information about the solubility of CI994 (Tacedinaline) in water, the solubility of CI994 (Tacedinaline) in DMSO, the solubility of CI994 (Tacedinaline) in PBS buffer, the animal experiment(test) of CI994 (Tacedinaline), the in vivo,in vitro and clinical trial test of CI994 (Tacedinaline), the cell experiment(test) of CI994 (Tacedinaline), the IC50, EC50 and Affinity of CI994 (Tacedinaline) , please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC2060 CI994 (Tacedinaline) Tacedinaline (N-acetyldinaline) 是组蛋白脱乙酰酶(HDAC)的抑制剂,抑制重组HDAC 1, 2 and 3的 IC50 值分别为0.9,0.9,1.2 μM。