| References: |
Selective inhibitor of TGF-β signaling (IC50 = 0.85 μM); displays little or no inhibition of activin, Wnt or BMP signaling pathways. Induces proteasomal degradation of the TGF-β type II receptor. Inhibits TGF-β-induced mesoderm formation from mouse embryonic stem cells (ESCs) during early differentiation; selectively promotes the differentiation of ESCs to cardiomyocytes in vitro between days 3-5. Does not induce differentiation of vascular smooth muscle cells or endothelial cells. For the detailed information of ITD 1, the solubility of ITD 1 in water, the solubility of ITD 1 in DMSO, the solubility of ITD 1 in PBS buffer, the animal experiment (test) of ITD 1, the cell expriment (test) of ITD 1, the in vivo, in vitro and clinical trial test of ITD 1, the EC50, IC50,and affinity,of ITD 1, Please contact DC Chemicals. |
