| Cas No.: | 1092351-67-1 |
| 名称: | 2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol |
| 别名: | TORKinib,PP242; PP-242,PP 242 |
| SMILES: | N1C2=C(C=C(O)C=C2)C=C1C1C2=C(N)N=CN=C2N(C(C)C)N=1 |
| 分子式: | C16H16N6O |
| 分子量: | 308.34 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | PP242 exhibits potent selectivity For mTOR over other PI3K family kinases such as p110α, p110β, p110γ, p110δ, and DNA-PK with IC50 of 1.96 μM, 2.2 μM, 1.27 μM, 0.102 μM, and 0.408 μM, respectively. PP242 displays some inhibitory activity against Ret, PKC |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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