| Cas No.: | 1062368-62-0 |
| 名称: | 4-[6-(4-Piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline hydrochloride |
| 别名: | LDN-193189 HCl,LDN 193189 HCl |
| SMILES: | N1C2C(=CC=CC=2)C(C2=C3N(N=C2)C=C(C2=CC=C(N4CCNCC4)C=C2)C=N3)=CC=1.[H]Cl |
| 分子式: | C25H22N6.HCl |
| 分子量: | 442.94 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | LDN193189 potently inhibits BMP4-mediated Smad1, Smad5 and Smad8 activation with IC50 of 5 nM, and efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively. Furthermore, LDN193189 al |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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