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In U-87MG cells, (R)-2-Hydroxyglutarate acts as weak antagonists of α-KG to inhibit α-KG-dependent histone demethylases and increases dimethylation on both H3K9 and H3K79. Besides, (R)-2-Hydroxyglutarate inhibits ATP synthase and mTOR signaling, and thus causes growth arrest and tumor cell killing. For the detailed information of Disodium (R)-2-Hydroxyglutarate, the solubility of Disodium (R)-2-Hydroxyglutarate in water, the solubility of Disodium (R)-2-Hydroxyglutarate in DMSO, the solubility of Disodium (R)-2-Hydroxyglutarate in PBS buffer, the animal experiment (test) of Disodium (R)-2-Hydroxyglutarate, the cell expriment (test) of Disodium (R)-2-Hydroxyglutarate, the in vivo, in vitro and clinical trial test of Disodium (R)-2-Hydroxyglutarate, the EC50, IC50,and affinity,of Disodium (R)-2-Hydroxyglutarate, For the detailed information of Disodium (R)-2-Hydroxyglutarate, the solubility of Disodium (R)-2-Hydroxyglutarate in water, the solubility of Disodium (R)-2-Hydroxyglutarate in DMSO, the solubility of Disodium (R)-2-Hydroxyglutarate in PBS buffer, the animal experiment (test) of Disodium (R)-2-Hydroxyglutarate, the cell expriment (test) of Disodium (R)-2-Hydroxyglutarate, the in vivo, in vitro and clinical trial test of Disodium (R)-2-Hydroxyglutarate, the EC50, IC50,and affinity,of Disodium (R)-2-Hydroxyglutarate, Please contact DC Chemicals. |