| References: |
GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, Kiapp is 21 nM for mTOR.GNE-477 is a potent dual PI3K/mTOR inhibitor that displays desirable pharmacokinetic properties in each of three species studied. GNE-477 also exhibited stasis in a PC3 tumor growth inhibition study.
For the detailed information of GNE 477, the solubility of GNE 477 in water, the solubility of GNE 477 in DMSO, the solubility of GNE 477 in PBS buffer, the animal experiment (test) of GNE 477, the cell expriment (test) of GNE 477, the in vivo, in vitro and clinical trial test of GNE 477, the EC50, IC50,and affinity,of GNE 477, For the detailed information of GNE 477, the solubility of GNE 477 in water, the solubility of GNE 477 in DMSO, the solubility of GNE 477 in PBS buffer, the animal experiment (test) of GNE 477, the cell expriment (test) of GNE 477, the in vivo, in vitro and clinical trial test of GNE 477, the EC50, IC50,and affinity,of GNE 477, Please contact DC Chemicals. |
