CVT-10216
产品编号: DC7391
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应用领域
CVT-10216 是一种高度选择性的可逆醛脱氢酶 2 (ALDH-2) 抑制剂,IC50 为 29 nM。 CVT-10216 还具有 ALDH-1 的抑制作用,IC50 为 1.3 μM。 CVT-10216 可以减少偏爱酒精的大鼠过量饮酒,并表现出抗焦虑作用。
Cas No.: |
1005334-57-5 |
名称: |
3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-1-benzopyran-7-yl]oxy]methyl]benzoic acid |
别名: |
CVT-10216,CVT 10216,CVT10216 |
SMILES: |
C(O)(=O)C1=CC=CC(COC2=CC=C3C(=C2)OC=C(C2=CC=C(NS(C)(=O)=O)C=C2)C3=O)=C1 |
分子式: |
C24H19NO7S |
分子量: |
465.47516 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vitro: |
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References: |
CVT-10216 is a highly selective, reversible inhibitor of ALDH-2 that reduces excessive alcohol drinking. For the detailed information of CVT-10216, the solubility of CVT-10216 in water, the solubility of CVT-10216 in DMSO, the solubility of CVT-10216 in P |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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