NSC95397 产品说明书 Chemicals
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产品编号 DC11691
名称 NSC95397

化学性质

CAS 93718-83-3
分子式 C14H14O4S2
分子量 310.38
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description CAS NO.：93718-83-3
Product Name：2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone
Synonyms：NSC-95397;NSC 95397
EINEC:
Molecular Formula：C14H14O4S2
Molecular Weight：310.38
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


A potent, selective, reversible Cdc25 dual specificity phosphatase inhibitor with Ki of 32/96/40 nM for Cdc25A/B/C, respectively; displays 125- and 180-fold selectivity over VH1-related dual-specificity phosphatase and PTP1B; shows significant growth inhibition in cancer cells and blocks G(2)/M phase transition; also inhibits cellular MKP-1 and MKP-3 with IC50 of 13 uM.
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