2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
Oritavancin, also known as LY333328 and Orbactiv, is a novel semisynthetic glycopeptide antibiotics. On August 6, 2014, the FDA approved oritavancin for treatment of skin infections. Oritavancin possesses potent and rapid bactericidal activity in vitro against a broad spectrum of both resistant and susceptible Gram-positive bacteria, including Staphylococcus aureus, MRSA, enterococci, and streptococci. Oritavancin was more active than either metronidazole or vancomycin against strains of Clostridium difficile tested. Oritavancin has potential use as a therapy for exposure to Bacillus anthracis, the Gram-positive bacterium that causes anthrax, having demonstrated efficacy in a mouse model both before and after exposure to the bacterium. The 4'-chlorobiphenylmethyl group disrupts the cell membrane of Gram-positive bacteria. It also acts by inhibition of transglycosylation and inhibition of transpeptidation For the detailed information of Oritavancin Diphosphate（LY333328, Orbactiv）, the solubility of Oritavancin Diphosphate（LY333328, Orbactiv） in water, the solubility of Oritavancin Diphosphate（LY333328, Orbactiv） in DMSO, the solubility of Oritavancin Diphosphate（LY333328, Orbactiv） in PBS buffer, the animal experiment (test) of Oritavancin Diphosphate（LY333328, Orbactiv）, the cell expriment (test) of Oritavancin Diphosphate（LY333328, Orbactiv）, the in vivo, in vitro and clinical trial test of Oritavancin Diphosphate（LY333328, Orbactiv）, the EC50, IC50,and affinity,of Oritavancin Diphosphate（LY333328, Orbactiv）, For the detailed information of Oritavancin Diphosphate（LY333328, Orbactiv）, the solubility of Oritavancin Diphosphate（LY333328, Orbactiv） in water, the solubility of Oritavancin Diphosphate（LY333328, Orbactiv） in DMSO, the solubility of Oritavancin Diphosphate（LY333328, Orbactiv） in PBS buffer, the animal experiment (test) of Oritavancin Diphosphate（LY333328, Orbactiv）, the cell expriment (test) of Oritavancin Diphosphate（LY333328, Orbactiv）, the in vivo, in vitro and clinical trial test of Oritavancin Diphosphate（LY333328, Orbactiv）, the EC50, IC50,and affinity,of Oritavancin Diphosphate（LY333328, Orbactiv）, Please contact DC Chemicals.
