TG101348(Fedratinib) 产品说明书 Chemicals
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产品编号 DC7318
名称 TG101348(Fedratinib)

化学性质

CAS 936091-26-8
分子式 C27H36N6O3S
分子量 524.68
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


TG-101348 also significantly inhibits JAK2 V617F, Flt3, and Ret with IC50 of 3 nM, 15 nM, and 48 nM, respectively. TG101348 has an IC50 ~300-fold higher For the closely related JAK3 and is a less potent inhibitor of the JAK1 and TYK2 family members. TG10
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