Verdiperstat (AZD3241) 产品说明书 Chemicals
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产品编号 DC12267
名称 Verdiperstat (AZD3241)

化学性质

CAS 890655-80-8
分子式 C11H15N3O2S
分子量 253.32
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


In Vitro Verdiperstat (AZD3241) is a myeloperoxidase (MPO) inhibitor, with an IC50 of 630 nM, and is used in the research of neurodegenerative brain disorders. Verdiperstat selectively and irreversibly inhibits myeloperoxidase, and may involves reduction of oxidative stress leading to reduction of sustained neuroinflammation.
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