Rocaglamide (Rocaglamide A; Roc-A) 产品说明书 Chemicals
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产品编号 DC28015
名称 Rocaglamide (Rocaglamide A; Roc-A)

化学性质

CAS 84573-16-0
分子式 C29H31NO7
分子量 505.55
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Rocaglamide is a natural product which belongs to a class of molecules called flavaglines.[1][2] This compound was isolated in 1982 by King and colleagues based on its antileukemic activity.[3] Like other flavaglines, rocaglamide displays potent insecticidal, antifungal, anti-inflammatory and anticancer activities. Rocaglamide A (RocA) inhibits eukaryotic translation initiation by binding to the translation initiation factor eIF4A and converting it into a translational repressor.[4]
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