NGI-1 (ML414) 产品说明书 Chemicals
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产品编号 DC11281
名称 NGI-1 (ML414)

化学性质

CAS 790702-57-7
分子式 C17H22N4O3S2
分子量 394.51
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Novel cell-permeable inhibitor of oligosaccharyltransferase (OST), blocking cell-surface localization and signaling of the epidermal growth factor receptor (EGFR) glycoprotein in non-small-cell lung cancer cells, but selectively arresting proliferation in only those cell lines that are dependent on EGFR (or fibroblast growth factor, FGFR) for survival
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