A77-01 产品说明书 Chemicals
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产品编号 DC8020
名称 A77-01

化学性质

CAS 607737-87-1
分子式 C18H14N4
分子量 286.33
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.A-77-01 is a close analogue of A-83-01(Axon 1421) and has a very similar biological profile of A-83-01. A-83-01 is found to decompose to A-77-01 under certain circumstances and A-77-01 is likely an active component or metabolite of its prodrug A-83-01. For the detailed information of A77-01, the solubility of A77-01 in water, the solubility of A77-01 in DMSO, the solubility of A77-01 in PBS buffer, the animal experiment (test) of A77-01, the cell expriment (test) of A77-01, the in vivo, in vitro and clinical trial test of A77-01, the EC50, IC50,and affinity,of A77-01, Please contact DC Chemicals.
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