2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.A-77-01 is a close analogue of A-83-01(Axon 1421) and has a very similar biological profile of A-83-01. A-83-01 is found to decompose to A-77-01 under certain circumstances and A-77-01 is likely an active component or metabolite of its prodrug A-83-01.
For the detailed information of A77-01, the solubility of A77-01 in water, the solubility of A77-01 in DMSO, the solubility of A77-01 in PBS buffer, the animal experiment (test) of A77-01, the cell expriment (test) of A77-01, the in vivo, in vitro and clinical trial test of A77-01, the EC50, IC50,and affinity,of A77-01, Please contact DC Chemicals.