T-5224 产品说明书 Chemicals
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产品编号 DC8024
名称 T-5224

化学性质

CAS 530141-72-1
分子式 C29H27NO8
分子量 517.53
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


T-5224 is a selective inhibitor of c-Fos/activator protein (AP)-1, attenuates lipopolysaccharide-induced liver injury in mice.T-5224 was converted to its acyl O-glucuronide (G2) by UGT1A1 and UGT1A3 and to its hydroxyl O-glucuronide (G3) by several UGTs, but it was not metabolized by the P450s . For the detailed information of T-5224, the solubility of T-5224 in water, the solubility of T-5224 in DMSO, the solubility of T-5224 in PBS buffer, the animal experiment (test) of T-5224, the cell expriment (test) of T-5224, the in vivo, in vitro and clinical trial test of T-5224, the EC50, IC50,and affinity,of T-5224, Please contact DC Chemicals.
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