α-Amyloid Precursor Protein Modulator 产品说明书 Chemicals
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产品编号 DC8534
名称 α-Amyloid Precursor Protein Modulator

化学性质

CAS 497259-23-1
分子式 C27H30F3N3O3
分子量 501.55
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


α-Amyloid Precursor Protein Modulator is a cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblast AG06848. α-Amyloid Precursor Protein Modulator displays a marked loss of tumor promoting activity.A cell-permeable benzolactam derived PKC activator
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