NS6180 产品说明书 Chemicals
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产品编号 DC8269
名称 NS6180

化学性质

CAS 353262-04-1
分子式 C16H12F3NOS
分子量 323.33
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


NS6180 is a novel inhibitor of the intermediate-conductance Ca2+-activated K+ channel (KCa3.1) The IC50 of NS6180 against cloned human KCa3.1 is 9 nM. The compound blocks proliferation and production of IL-2 and IFNγ with sub-micromolar potencies in either ConA or PMA/ionomycin challenged rat splenocytes. For the detailed information of NS6180, the solubility of NS6180 in water, the solubility of NS6180 in DMSO, the solubility of NS6180 in PBS buffer, the animal experiment (test) of NS6180, the cell expriment (test) of NS6180, the in vivo, in vitro and clinical trial test of NS6180, the EC50, IC50,and affinity,of NS6180, For the detailed information of NS6180, the solubility of NS6180 in water, the solubility of NS6180 in DMSO, the solubility of NS6180 in PBS buffer, the animal experiment (test) of NS6180, the cell expriment (test) of NS6180, the in vivo, in vitro and clinical trial test of NS6180, the EC50, IC50,and affinity,of NS6180, Please contact DC Chemicals.
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