2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
Stat5 Inhibitor is a cell permeable nonpetidic nicotinoyl hydrazone which suppresses Stat5 via binding to the SH2 domain. Studies indicate that Stat5 Inhibitor suppresses the SH2 domain of Stat1 and Stat3 to a lesser extent than Stat5 inhibition. In addition, Stat5/Stat5 DNA binding in K562 nuclear extracts are inhibited by Stat5 Inhibitor. Stat5 functions biologically in various processes such as homeostasis of hematopoietic stem cells, development of blood cells, growth hormone effects, and differentiation of mammary epithelium.
