GW-7647 产品说明书 Chemicals
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产品编号 DC2078
名称 GW-7647

化学性质

CAS 265129-71-3
分子式 C29H46N2O3S
分子量 502.75
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


GW 7647 is a potent PPARα agonist with 200-fold selectivity over PPARγ and PPARδ. This compound has also been found to cause an up-regulation of β-oxidation gene expression and an increase in palmitate oxidation. Additionally, glycolysis is strongly reduced at transcriptional levels by GW 7647 leading to a decrease in lactate and pyruvate production. Furthermore, this agent displays the ability to decrease glucose oxidation and inhibit lipogenesis and triglyceride esterification. For the detailed information about the solubility of GW-7647 in water, the solubility of GW-7647 in DMSO, the solubility of GW-7647 in PBS buffer, the animal experiment(test) of GW-7647,the in vivo,in vitro and clinical trial test of GW-7647,the cell experiment(test) of GW-7647,the IC50, EC50 and Affinity of GW-7647, please contact DC Chemicals.
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