Cyclo(RGDyK) 产品说明书 Chemicals
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产品编号 DC8399
名称 Cyclo(RGDyK)

化学性质

CAS 250612-42-1
分子式 C31H43F6N9O12
分子量 847.72
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Cyclo(RGDyK) shows high affinity and selectivity for αVβ3 over αVβ5 and αIIbβ3. Cyclo(RGDyK)-conjugated micelles (TPM) facilitated the cell-specific uptake of DiI into B16-F10 cells and HUVECs via integrin-mediated endocytosis compared with Cyclo(RGDyK) -free micelles (NPM). In apoE−/− mice, Cyclo(RGDyK) (1 nmol, i.v.) inhibits the increase of αVβ3 integrin expression in the intima of the left stenotic carotid artery. For the detailed information of Cyclo(RGDyK), the solubility of Cyclo(RGDyK) in water, the solubility of Cyclo(RGDyK) in DMSO, the solubility of Cyclo(RGDyK) in PBS buffer, the animal experiment (test) of Cyclo(RGDyK), the cell expriment (test) of Cyclo(RGDyK), the in vivo, in vitro and clinical trial test of Cyclo(RGDyK), the EC50, IC50,and affinity,of Cyclo(RGDyK), For the detailed information of Cyclo(RGDyK), the solubility of Cyclo(RGDyK) in water, the solubility of Cyclo(RGDyK) in DMSO, the solubility of Cyclo(RGDyK) in PBS buffer, the animal experiment (test) of Cyclo(RGDyK), the cell expriment (test) of Cyclo(RGDyK), the in vivo, in vitro and clinical trial test of Cyclo(RGDyK), the EC50, IC50,and affinity,of Cyclo(RGDyK), Please contact DC Chemicals.
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