KI8751 产品说明书 Chemicals
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产品编号 DC7440
名称 KI8751

化学性质

CAS 228559-41-9
分子式 C24H18F3N3O4
分子量 469.41
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Ki8751 potently and selectively inhibits VEGFR2 with IC50 of 0.9 nM. Ki8751 also inhibits PDGFRα, c-Kit, and FGFR-2, with much higher IC50 values (40 nM–170 nM). Except For these several kinases, Ki8751 doesn't disturb other kinases, including HGFR, EGFR
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