2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
RITA is an anti-tumor agent that binds wild-type p53 (Kd = 1.5 nM) preventing p53-MDM2 (HDM2) interaction. Induces p53 accumulation and stimulates apoptosis in tumor cell lines expressing wild-type p53 in vitro and in vivo. Inhibits HPV-E6-mediated proteasomal degradation. Suppresses expression of cervical carcinoma HeLa xenografts in vivo. For the detailed information about the solubility of RITA (NSC 652287) in water, the solubility of RITA (NSC 652287) in DMSO, the solubility of RITA (NSC 652287) in PBS buffer, the animal experiment（test） of RITA (NSC 652287),the in vivo,in vitro and clinical trial test of RITA (NSC 652287),the cell experiment（test） of RITA (NSC 652287),the IC50, EC50 and Affinity of RITA (NSC 652287), please contact DC Chemicals.
