2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
Janex 1 selectively inhibits the tyrosine kinase activity of JAK3 with an IC50 value of 78 µM without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases (IC50 ≥350 µM).Janex 1 induces apoptosis in JAK3-expressing human leukemia cell lines NALM-6 and LC1;19, but not in melanoma or squamous carcinoma cell lines. For the detailed information of WHI-P131(Janex 1), the solubility of WHI-P131(Janex 1) in water, the solubility of WHI-P131(Janex 1) in DMSO, the solubility of WHI-P131(Janex 1) in PBS buffer, the animal experiment (test) of WHI-P131(Janex 1), the cell expriment (test) of WHI-P131(Janex 1), the in vivo, in vitro and clinical trial test of WHI-P131(Janex 1), the EC50, IC50,and affinity,of WHI-P131(Janex 1), For the detailed information of WHI-P131(Janex 1), the solubility of WHI-P131(Janex 1) in water, the solubility of WHI-P131(Janex 1) in DMSO, the solubility of WHI-P131(Janex 1) in PBS buffer, the animal experiment (test) of WHI-P131(Janex 1), the cell expriment (test) of WHI-P131(Janex 1), the in vivo, in vitro and clinical trial test of WHI-P131(Janex 1), the EC50, IC50,and affinity,of WHI-P131(Janex 1), Please contact DC Chemicals.
