2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
Anacardic Acid is a pentadecane aliphatic chain containing hydroxylcarboxylic acid. The acid is an effective inhibitor of the activities of p300, p300/CBP associated factor histone acetyltransferase, prostaglandin synthase (PTGS2 or Cox-2), tyrosinase, urease-α and -β, lipoxygenase (LO), and xanthine oxidase. Additionally, it has been shown to potently inhibit HAT-dependent transcription and SUMOylation, as well as decrease expression of NF-κB regulated gene products at high concentrations. Research suggests that anacardic acid is a potent activator of ARK-1 (Aurora kinase A) mediated phosphorylation of histone H3 while leaving ARK-2 unaffected in vitro. Anacardic acid has demonstrated bactericidal activity against methicillin-resistant Staphylococcus aureus (MRSA). For the detailed information of Anacardic Acid, the solubility of Anacardic Acid in water, the solubility of Anacardic Acid in DMSO, the solubility of Anacardic Acid in PBS buffer, the animal experiment (test) of Anacardic Acid, the cell expriment (test) of Anacardic Acid, the in vivo, in vitro and clinical trial test of Anacardic Acid, the EC50, IC50,and affinity,of Anacardic Acid, For the detailed information of Anacardic Acid, the solubility of Anacardic Acid in water, the solubility of Anacardic Acid in DMSO, the solubility of Anacardic Acid in PBS buffer, the animal experiment (test) of Anacardic Acid, the cell expriment (test) of Anacardic Acid, the in vivo, in vitro and clinical trial test of Anacardic Acid, the EC50, IC50,and affinity,of Anacardic Acid, Please contact DC Chemicals.
